Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 16/20 | 0.79 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260545 | 0.96 | MCHR1 (0.73) | MCHR1DGAT1MEN1NPC1RAB9A | |
| SCHEMBL7254564 | 0.91 | MCHR1 (0.81) | MCHR1DGAT1MEN1NPC1RAB9A | |
| SCHEMBL5582671 | 0.91 | MCHR1 (0.83) | MCHR1DGAT1MEN1NPC1RAB9A | |
| SCHEMBL7254682 | 0.89 | MCHR1 (0.76) | MCHR1DGAT1MEN1NPC1RAB9A | |
| SCHEMBL7254656 | 0.89 | MCHR1 (0.76) | MCHR1DGAT1MEN1NPC1RAB9A | |
| SCHEMBL7258533 | 0.89 | MCHR1 (0.72) | MCHR1DGAT1MEN1NPC1RAB9A | |
| SCHEMBL7255010 | 0.89 | MCHR1 (0.75) | MCHR1DGAT1MEN1NPC1RAB9A | |
| SCHEMBL7255872 | 0.89 | MCHR1 (1.00) | MCHR1DGAT1MEN1NPC1RAB9A | |
| SCHEMBL7254920 | 0.88 | MCHR1 (0.71) | MCHR1DGAT1MEN1NPC1RAB9A | |
| SCHEMBL7260602 | 0.88 | MCHR1 (0.74) | MCHR1DGAT1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087046-A1 | NOVEL AMINOTETRALINE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |