SCHEMBL7255694

SCHEMBL7255694

C[C@H](CCCOc1cccc(-c2ccccc2)c1)Oc1cccc2ccc(N)nc12

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5883717 1.00 MCHR1 (0.60) MCHR1
SCHEMBL5884490 0.89 MCHR1 (0.65) MCHR1
SCHEMBL5884167 0.88 MCHR1 (0.57) MCHR1
SCHEMBL5884580 0.87 MCHR1 (0.62) MCHR1
SCHEMBL5884175 0.87 MCHR1 (0.62) MCHR1
SCHEMBL5884224 0.86 MCHR1 (0.61) MCHR1
SCHEMBL5884234 0.86 MCHR1 (0.61) MCHR1
SCHEMBL5884293 0.86 MCHR1 (0.61) MCHR1
SCHEMBL5884118 0.86 MCHR1 (0.61) MCHR1
SCHEMBL5884085 0.84 MCHR1 (0.74) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003105850-A1 2-AMINOQUINOLINES AS MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS ABBOTT LABORATORIES (US) 2003-12-24 WO disclosed