Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145742 | 0.84 | CHEK1 (0.61) | CHEK1KDR | |
| SCHEMBL146578 | 0.84 | CHEK1 (0.61) | CHEK1KDR | |
| SCHEMBL144138 | 0.82 | CHEK1 (0.66) | CHEK1KDR | |
| SCHEMBL146846 | 0.82 | CHEK1 (0.66) | CHEK1KDR | |
| SCHEMBL5078744 | 0.81 | CHEK1 (0.66) | CHEK1KDR | |
| SCHEMBL144982 | 0.80 | CHEK1 (0.76) | CHEK1KDR | |
| SCHEMBL5082047 | 0.79 | CHEK1 (0.75) | CHEK1KDR | |
| SCHEMBL5385089 | 0.79 | CHEK1 (0.72) | CHEK1KDR | |
| SCHEMBL5385085 | 0.79 | CHEK1 (0.72) | CHEK1KDR | |
| SCHEMBL5081972 | 0.79 | CHEK1 (0.69) | CHEK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020699-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-03-13 | — | — | WO | claimed |