Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 18/20 | 0.88 |
| ▸ | KLKB1 | P03952 | 11/20 | 0.73 |
| ▸ | F3 | P13726 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7252727 | 0.99 | F7 (0.87) | F7KLKB1F3 | |
| SCHEMBL7258358 | 0.91 | F7 (0.88) | F7KLKB1F3 | |
| SCHEMBL6395167 | 0.91 | F7 (0.87) | F7KLKB1F3 | |
| SCHEMBL6388048 | 0.90 | F7 (0.88) | F7KLKB1F3 | |
| SCHEMBL6397030 | 0.90 | KLKB1 (0.88) | F7KLKB1F3 | |
| SCHEMBL7252686 | 0.90 | F7 (0.88) | F7KLKB1F3 | |
| SCHEMBL7258122 | 0.89 | F7 (0.88) | F7KLKB1F3 | |
| SCHEMBL7253460 | 0.89 | KLKB1 (0.88) | F7KLKB1F3 | |
| SCHEMBL6393585 | 0.89 | F3 (0.73) | F7KLKB1F3 | |
| SCHEMBL7253486 | 0.88 | F7 (0.75) | F7KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006670-A2 | 2-[5-(5-CARBAMIMIDOYL-1H-HETEROARYL)-6-HYDROXYBIPHENYL-3-YL]-SUCCINIC ACID DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006670-A2 | 2-[5-(5-CARBAMIMIDOYL-1H-HETEROARYL)-6-HYDROXYBIPHENYL-3-YL]-SUCCINIC ACID DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-01-23 | — | — | WO | disclosed |