Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 15/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6133923 | 0.85 | ADORA1 (0.47) | ADORA1ADORA2AHTT | |
| SCHEMBL6134167 | 0.84 | ADORA1 (0.45) | ADORA1ADORA2AHSD17B10 | |
| SCHEMBL6133381 | 0.82 | POLB (0.48) | ADORA1ADORA2AMAPTNPSR1 | |
| SCHEMBL6134324 | 0.81 | ADORA1 (0.47) | ADORA1ADORA2A | |
| SCHEMBL6133393 | 0.81 | ADORA1 (0.48) | ADORA1ADORA2AMAPTNPSR1 | |
| SCHEMBL6133471 | 0.79 | ADORA1 (0.50) | ADORA1ADORA2A | |
| SCHEMBL6133694 | 0.77 | ADORA1 (0.46) | ADORA1ADORA2AMAPTNPSR1 | |
| SCHEMBL6133912 | 0.75 | ADORA1 (0.44) | ADORA1ADORA2A | |
| SCHEMBL6133581 | 0.73 | ADORA1 (0.49) | ADORA1ADORA2AHTTMAPT | |
| SCHEMBL6539249 | 0.72 | TP53 (0.40) | KDM4EHSD17B10HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057689-A1 | AMINOPYRIMIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-17 | — | — | WO | disclosed |