Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 16/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.56 |
| ▸ | DPP4 | P27487 | 7/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.56 |
| ▸ | FAP | Q12884 | 1/20 | 0.45 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175043 | 1.00 | DPP7 (0.56) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL6175048 | 1.00 | DPP7 (0.56) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL6165300 | 0.83 | DPP7 (0.39) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL7418737 | 0.83 | DPP7 (0.39) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL6492871 | 0.83 | DPP7 (0.39) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL6174604 | 0.81 | DPP4 (0.40) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL7189181 | 0.81 | DPP4 (0.40) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL6174600 | 0.81 | DPP4 (0.40) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL7186525 | 0.81 | DPP7 (0.37) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL6488699 | 0.81 | DPP7 (0.37) | DPP7DPP8DPP4DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057144-A2 | CHANGE INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS (US) | 2003-07-17 | — | — | WO | disclosed |