Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | MTTP | P55157 | 15/20 | 0.42 |
| ▸ | APOB | P04114 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036636 | 0.90 | MTTP (0.43) | TRPV4MTTPAPOBGAASMN1; SMN2 | |
| SCHEMBL6678823 | 0.83 | MTTP (0.47) | MTTPAPOBGAASMN1; SMN2 | |
| SCHEMBL6673783 | 0.83 | MTTP (0.48) | TRPV4MTTPAPOBGAASMN1; SMN2 | |
| SCHEMBL6677178 | 0.83 | MTTP (0.47) | MTTPAPOBGAASMN1; SMN2 | |
| SCHEMBL6674929 | 0.83 | MTTP (0.49) | MTTPAPOBGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL6680172 | 0.81 | MTTP (0.46) | TRPV4MTTPAPOB | |
| SCHEMBL7258136 | 0.81 | MTTP (0.43) | TRPV4MTTPAPOBGAASMN1; SMN2 | |
| SCHEMBL6673930 | 0.80 | MTTP (0.51) | MTTPAPOBGAASMN1; SMN2 | |
| SCHEMBL6674644 | 0.78 | MTTP (0.45) | MTTPAPOBGAASMN1; SMN2 | |
| SCHEMBL7253319 | 0.78 | MTTP (0.50) | MTTPAPOBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004020-A1 | HETEROARYL CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND THE USE OF THE SAME AS INHIBITORS OF THE MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-01-16 | — | — | WO | disclosed |