Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258749 | 0.79 | SLC6A4 (0.46) | AOC3HTR2A | |
| SCHEMBL3462477 | 0.75 | TAAR1 (0.59) | TAAR1AOC3HTR2AHTR1AHTR2C | |
| SCHEMBL3064919 | 0.72 | TAAR1 (0.61) | TAAR1AOC3HTR2AHTR1AHTR2C | |
| SCHEMBL3060544 | 0.72 | TAAR1 (0.61) | TAAR1AOC3HTR2AHTR1AHTR2C | |
| SCHEMBL3064865 | 0.72 | TAAR1 (0.61) | TAAR1AOC3HTR2AHTR1AHTR2C | |
| SCHEMBL14196710 | 0.72 | SLC6A4 (0.40) | AOC3HTR2A | |
| SCHEMBL2155236 | 0.72 | TAAR1 (0.50) | TAAR1AOC3HTR2AHTR1AHTR2C | |
| SCHEMBL3056915 | 0.71 | TAAR1 (0.59) | TAAR1AOC3HTR2AHTR1AHTR2C | |
| SCHEMBL3052939 | 0.71 | TAAR1 (1.00) | TAAR1AOC3HTR2AHTR1AHTR2C | |
| SCHEMBL3052936 | 0.71 | TAAR1 (1.00) | TAAR1HTR2AHTR1AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614898-B1 | INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6291470-B1 | DELTA-OPIOID ANTAGONIST HAVING HIGH SELECTIVITY AND ACTIVITY, THAT EXHIBITS IMMUNOSUPPRESSIVE ACTION, ANTIALLERGIC ACTION, ANTI-INFLAMMATORY ACTION AND BRAIN CELL-PROTECTING ACTION | TORAY INDUSTRIES, INC. (JP) | 2001-09-18 | — | — | US | disclosed |
| US-6087369-A | AN IMMUNOSUPPRESSIVE AGENT, ANTIALLERGIC AGENT, ANTI-INFLAMMATORY AGENT AND BRAIN CELL-PROTECTING AGENT | TORAY INDUSTRIES, LTD. (JP) | 2000-07-11 | — | — | US | disclosed |
| EP-0614898-A1 | INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1994-09-14 | — | — | EP | disclosed |