Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259411 | 0.82 | SIRT2 (0.47) | SIRT2CYP11B1CYP11B2ENPP2SIGMAR1 | |
| SCHEMBL2490264 | 0.80 | SIRT2 (0.48) | SIRT2MAOACYP11B1CYP11B2ENPP2 | |
| Hydrochloric Acid SCHEMBL7988290 | 0.79 | SIRT2 (0.47) | SIRT2MAOACYP11B1CYP11B2ENPP2 | |
| SCHEMBL2796109 | 0.79 | SIRT2 (0.52) | SIRT2CYP11B1CYP11B2 | |
| SCHEMBL8165853 | 0.79 | SIRT2 (0.47) | SIRT2MAOACYP11B1CYP11B2ENPP2 | |
| SCHEMBL1309013 | 0.79 | SIRT2 (0.47) | SIRT2CYP11B1CYP11B2ENPP2 | |
| SCHEMBL2032778 | 0.79 | SIRT2 (0.47) | SIRT2CYP11B1CYP11B2ENPP2 | |
| SCHEMBL8794940 | 0.79 | SIRT2 (0.49) | SIRT2MAOACYP11B1CYP11B2ENPP2 | |
| SCHEMBL4682888 | 0.78 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2ENPP2 | |
| SCHEMBL7987099 | 0.78 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003011856-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2003-02-13 | — | — | WO | disclosed |