Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.70 |
| ▸ | CYCS | P99999 | 3/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 4/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30616034 | 1.00 | TOP1 (0.70) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL28008849 | 0.98 | TOP1 (0.72) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL3999312 | 0.98 | TOP1 (0.72) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL28022267 | 0.98 | TOP1 (0.72) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL29962487 | 0.98 | TOP1 (0.72) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL27899186 | 0.98 | TOP1 (0.72) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL30616040 | 0.98 | TOP1 (0.72) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL29520899 | 0.97 | TOP1 (0.70) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL28644858 | 0.97 | TOP1 (0.70) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL3802533 | 0.93 | TOP1 (0.79) | TOP1CYCSSTAT3STAT1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891977-B1 | 5-(4-Hydroxyphenyl)-porphyrin derivatives as photosensitisers | DLR EV (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6107480-A | 5-(HYDROXYLATEDPHENYL) PORPHYRIN DERIVATIVES WHICH MAY BE COVALENTLY BONDED TO SPECIFIED POLYMERS VIA THE HYDROXYLATED PHENYL GROUP; USE AS PHOTOSENSITIZERS FOR THE CATALYTIC FORMATION OF SINGLET OXYGEN | DLR, DEUTSCHE ZENTRUM FUR LUFT UND RAUMFAHRT E.V. (DE) | 2000-08-22 | — | — | US | disclosed |
| EP-0891977-A1 | 5-(4-Hydroxyphenyl)-porphyrin derivatives as photosensitisers | DLR Deutsches Zentrum für Luft- und Raumfahrt e.V. (DE) | 1999-01-20 | — | — | EP | disclosed |