Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 13/20 | 1.00 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.84 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.81 |
| ▸ | ACE | P12821 | 1/20 | 0.81 |
| ▸ | HTR2A | P28223 | 1/20 | 0.81 |
| ▸ | FAP | Q12884 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725863 | 1.00 | DPP4 (1.00) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL31268268 | 1.00 | DPP4 (1.00) | DPP4DPP8DPP9DPP7ACE | |
| Phosphoric Acid SCHEMBL14687901 | 0.96 | DPP4 (0.93) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3844850 | 0.95 | DPP4 (0.91) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL15024074 | 0.93 | DPP4 (1.00) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL12323237 | 0.93 | DPP4 (1.00) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3840450 | 0.92 | DPP4 (0.84) | DPP4DPP8DPP9DPP7ACE | |
| Hydrochloric Acid SCHEMBL28963694 | 0.92 | DPP4 (0.98) | DPP4DPP8DPP9DPP7ACE | |
| Sitagliptin SCHEMBL17783 | 0.89 | DPP4 (1.00) | DPP4DPP8DPP9DPP7ACE | |
| Sitagliptin SCHEMBL174489 | 0.89 | DPP4 (1.00) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609099-A2 | SITAGLIPTIN, SALTS AND POLYMORPHS THEREOF | USV Limited (IN) | 2013-07-03 | — | — | EP | claimed |
| WO-2012025944-A2 | SITAGLIPTIN, SALTS AND POLYMORPHS THEREOF | USV LIMITED (IN) | 2012-03-01 | — | — | WO | claimed |
| EP-2609099-A2 | SITAGLIPTIN, SALTS AND POLYMORPHS THEREOF | USV Limited (IN) | 2013-07-03 | — | — | EP | disclosed |
| US-20130158265-A1 | SITAGLIPTIN, SALTS AND POLYMORPHS THEREOF | USV LIMITED (IN) | 2013-06-20 | — | — | US | disclosed |
| WO-2012025944-A2 | SITAGLIPTIN, SALTS AND POLYMORPHS THEREOF | USV LIMITED (IN) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158265-A1 | SITAGLIPTIN, SALTS AND POLYMORPHS THEREOF | DPP4, DPP3, DPP9 | DPP4 1/4885DPP8 5/4885DPP9 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.