SCHEMBL7258735

SCHEMBL7258735

N#Cc1ccc(Cn2cncc2CNC(=O)c2ccccc2-c2ccc(C(=O)N3CCSCC3)o2)cc1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 15/20 0.52
FNTB P49356 15/20 0.52
PGGT1B P53609 5/20 0.50
KCNH2 Q12809 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7258738 0.88 FNTA (0.49) FNTAFNTBPGGT1BKCNH2
SCHEMBL7255082 0.81 FNTA (0.49) FNTAFNTBPGGT1B
SCHEMBL7258737 0.79 CYP11B1 (0.42) FNTAFNTBPGGT1BKCNH2
SCHEMBL7255190 0.79 FNTA (0.49) FNTAFNTBPGGT1B
SCHEMBL6986080 0.76 FNTA (0.61) FNTAFNTBPGGT1BKCNH2
SCHEMBL6983280 0.76 FNTA (0.60) FNTAFNTBPGGT1BKCNH2
SCHEMBL6980183 0.73 FNTA (0.58) FNTAFNTBPGGT1BKCNH2
SCHEMBL6984976 0.73 FNTA (0.57) FNTAFNTBPGGT1BKCNH2
SCHEMBL7259745 0.72 FNTA (0.40) FNTAFNTBPGGT1BKCNH2
SCHEMBL7259664 0.71 CYP11B1 (0.43) FNTAFNTBPGGT1BKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003099812-A1 PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE PIERRE FABRE MEDICAMENT (FR) 2003-12-04 WO disclosed