Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105086 | 1.00 | ITGB1 (0.56) | ITGB1ITGA4APP | |
| SCHEMBL7264611 | 0.97 | ITGB1 (0.56) | ITGB1ITGA4APP | |
| SCHEMBL7264602 | 0.97 | ITGB1 (0.56) | ITGB1ITGA4APP | |
| SCHEMBL7103715 | 0.95 | ITGB1 (0.60) | ITGB1ITGA4APP | |
| SCHEMBL7103720 | 0.95 | ITGB1 (0.60) | ITGB1ITGA4APP | |
| SCHEMBL7104260 | 0.94 | ITGB1 (0.53) | ITGB1ITGA4 | |
| SCHEMBL7104250 | 0.94 | ITGB1 (0.53) | ITGB1ITGA4 | |
| SCHEMBL7099885 | 0.92 | ITGB1 (0.51) | ITGB1ITGA4 | |
| SCHEMBL7099878 | 0.92 | ITGB1 (0.51) | ITGB1ITGA4 | |
| SCHEMBL7102804 | 0.92 | ITGB1 (0.53) | ITGB1ITGA4APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518283-B1 | To modify integrin function in such a way as to beneficially modulate cell adhesion | CELLTECH R&D LIMITED (GB) | 2003-02-11 | — | — | US | disclosed |