Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637487 | 0.92 | TSHR (0.59) | TSHRHPGDATMHCAR2ALDH1A1 | |
| SCHEMBL4374381 | 0.89 | TSHR (0.44) | TSHRATMALDH1A1CYP3A4RECQL | |
| Acrylic Acid SCHEMBL5062877 | 0.88 | TSHR (0.45) | TSHRATMALDH1A1CYP3A4RECQL | |
| SCHEMBL10953040 | 0.88 | TSHR (0.52) | TSHRHPGDATMHCAR2ALDH1A1 | |
| SCHEMBL6133965 | 0.85 | TSHR (0.72) | TSHRHPGDATMHCAR2ALDH1A1 | |
| SCHEMBL10904175 | 0.84 | ATM (0.56) | TSHRHPGDATMHCAR2ALDH1A1 | |
| SCHEMBL10904179 | 0.84 | ATM (0.56) | TSHRHPGDATMHCAR2ALDH1A1 | |
| Acrylic Acid SCHEMBL16151343 | 0.84 | TSHR (0.67) | TSHRHPGDATMHCAR2ALDH1A1 | |
| SCHEMBL2275748 | 0.84 | TSHR (0.40) | TSHRATMALDH1A1CYP3A4RECQL | |
| SCHEMBL29396343 | 0.83 | TSHR (0.52) | TSHRHPGDATMHCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024432-A2 | DEVICE FOR TRANSDERMAL ADMINISTRATION FOR THE TREATMENT OF URINARY TRACT DISORDERS | SCHWARZ PHARMA AG (DE) | 2003-03-27 | — | — | WO | disclosed |