Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 6/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | PPIG | Q13427 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261448 | 0.83 | SERPINE1 (0.69) | SERPINE1KMT2A | |
| SCHEMBL7265924 | 0.83 | SERPINE1 (0.56) | SERPINE1KMT2AGAAKDM4EMEN1 | |
| SCHEMBL7260082 | 0.79 | SERPINE1 (0.72) | SERPINE1ALDH1A1 | |
| SCHEMBL7261418 | 0.79 | KMT2A (0.49) | SERPINE1ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL7261488 | 0.78 | SERPINE1 (0.58) | SERPINE1EPHX1ALDH1A1KMT2AGAA | |
| SCHEMBL7265948 | 0.77 | SERPINE1 (0.52) | SERPINE1KMT2AGAAMEN1SMN1; SMN2 | |
| SCHEMBL7264661 | 0.77 | SERPINE1 (0.55) | SERPINE1KMT2A | |
| SCHEMBL7265777 | 0.76 | SERPINE1 (0.77) | SERPINE1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7260075 | 0.74 | SERPINE1 (0.58) | SERPINE1EPHX1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7264716 | 0.74 | SERPINE1 (0.59) | SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080564-A1 | MENTHOL SUBSTITUTED ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |