Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265960 | 0.89 | MEN1 (0.33) | TDP1MEN1KMT2AGAACA14 | |
| SCHEMBL6888540 | 0.80 | TDP1 (0.37) | TDP1MEN1KMT2AGAACA14 | |
| SCHEMBL3289724 | 0.78 | TDP1 (0.44) | TDP1MEN1KMT2AGAACA14 | |
| SCHEMBL6890969 | 0.78 | TDP1 (0.33) | TDP1MEN1KMT2AGAACA14 | |
| SCHEMBL3162813 | 0.77 | TDP1 (0.69) | TDP1MEN1KMT2AGAANPSR1 | |
| SCHEMBL3288385 | 0.77 | TDP1 (0.49) | TDP1MEN1KMT2AGAACA14 | |
| SCHEMBL13327079 | 0.75 | TDP1 (0.60) | TDP1MEN1KMT2AGAACA14 | |
| SCHEMBL3288396 | 0.74 | TDP1 (0.53) | TDP1MEN1KMT2AGAACA14 | |
| SCHEMBL16349550 | 0.73 | TDP1 (0.57) | TDP1MEN1KMT2AGAACA14 | |
| SCHEMBL567298 | 0.71 | TDP1 (0.53) | TDP1MEN1KMT2AGAACA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583301-B1 | Bipolar; form complexes with polyanions; delivering bioactive substances such as nucleic acids to cells in vitro and in vivo | CELLTECH R & D LIMITED (GB) | 2003-06-24 | — | — | US | disclosed |