Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 16/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 13/20 | 0.48 |
| ▸ | CDK1 | P06493 | 7/20 | 0.48 |
| ▸ | CDK9 | P50750 | 3/20 | 0.48 |
| ▸ | CDK7 | P50613 | 2/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CCND1 | P24385 | 2/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259669 | 0.85 | CDK2 (0.55) | CDK2CCNE1CDK5CDK1CDK9 | |
| SCHEMBL2908707 | 0.83 | CDK2 (0.52) | CDK2CCNE1CDK5CDK1CDK9 | |
| SCHEMBL2908697 | 0.83 | CDK2 (0.52) | CDK2CCNE1CDK5CDK1CDK9 | |
| SCHEMBL3794926 | 0.76 | CDK2 (0.52) | CDK2CCNE1CDK5CDK1CDK9 | |
| SCHEMBL3444052 | 0.73 | CDK2 (0.39) | CDK2CCNE1CDK5CDK1CDK9 | |
| SCHEMBL3717049 | 0.71 | CDK2 (0.50) | CDK2CCNE1CDK5CDK1CDK9 | |
| SCHEMBL3444820 | 0.71 | BCDIN3D (0.35) | CDK2CCNE1CDK5CDK9CDK7 | |
| SCHEMBL3444444 | 0.70 | CDK2 (0.42) | CDK2CCNE1CDK5CDK1CDK9 | |
| SCHEMBL3724482 | 0.70 | CDK2 (0.51) | CDK2CCNE1CDK5CDK1CDK9 | |
| SCHEMBL3722157 | 0.69 | CDK2 (0.57) | CDK2CCNE1CDK5CDK1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082872-A1 | NOVEL PYRAZOLO[4,3-D]PYRIMIDINES, PROCESSES FOR THEIR PREPARATION AND METHODS FOR THERAPY | USTAV EXPERIMENTALNI BOTANIKY AV CR (INSTITUTE OF EXPERIMENTAL BOTANY ACADEMY OF SCIENCES OF THE CZECH REPUBLIC) (CZ) | 2003-10-09 | — | — | WO | disclosed |