SCHEMBL7262143

SCHEMBL7262143

CC(=O)Oc1ccc(-c2ccc(OC(C)=O)cc2C(=O)O)c(C(=O)O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.66
ALDH1A1 P00352 4/20 0.55
PKM P14618 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.54
HSD17B10 Q99714 3/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50
CFD P00746 1/20 0.49
LMNA P02545 3/20 0.48
HPGD P15428 2/20 0.47
ELANE P08246 1/20 0.47
CYP3A4 P08684 1/20 0.47
ESR1 P03372 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
HMGB1 P09429 1/20 0.47
TSHR P16473 1/20 0.47
GGT1 P19440 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9723788 0.88 BACE1 (0.59) KDM4EALDH1A1PKMSMN1; SMN2HSD17B10
Hydrochloric Acid SCHEMBL9723743 0.87 BACE1 (0.58) KDM4EALDH1A1PKMSMN1; SMN2HSD17B10
SCHEMBL4360840 0.86 KDM4E (0.73) KDM4EALDH1A1PKMHSD17B10MAPT
SCHEMBL30590995 0.86 KDM4E (0.51) KDM4EALDH1A1PKMSMN1; SMN2HSD17B10
SCHEMBL27594594 0.83 KDM4E (0.64) KDM4EALDH1A1PKMHSD17B10MAPT
SCHEMBL344505 0.83 KDM4E (0.74) KDM4EALDH1A1PKMHSD17B10MAPT
SCHEMBL344841 0.83 KDM4E (0.64) KDM4EALDH1A1PKMHSD17B10MAPT
SCHEMBL31364552 0.83 KDM4E (0.64) KDM4EALDH1A1PKMHSD17B10MAPT
SCHEMBL10501453 0.81 KDM4E (0.62) KDM4EALDH1A1PKMHSD17B10MAPT
SCHEMBL22129867 0.81 KDM4E (0.62) KDM4EALDH1A1PKMHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788526-B1 NEGATIVE BIREFRINGENT RIGID ROD POLYMER FILMS UNIV AKRON (US) 2003-08-20 EP disclosed
EP-0788526-A4 NEGATIVE BIREFRINGENT RIGID ROD POLYMER FILMS UNIV AKRON (US) 1998-01-07 EP disclosed
EP-0788526-A1 NEGATIVE BIREFRINGENT RIGID ROD POLYMER FILMS The University of Akron (US) 1997-08-13 EP disclosed
US-5580950-A POLYESTERS, POLYAMIDES, POLYAMIDEIMIDE, OR POLYESTERIMIDE THE UNIVERSITY OF AKRON (US) 1996-12-03 US disclosed
WO-1996011967-A1 NEGATIVE BIREFRINGENT RIGID ROD POLYMER FILMS THE UNIVERSITY OF AKRON (US) 1996-04-25 WO disclosed