Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256618 | 0.94 | KMT2A (0.53) | CA1CA2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL12948471 | 0.94 | MAPT (0.51) | CA1CA2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4686240 | 0.84 | SMN1; SMN2 (0.61) | CA1CA2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL5061591 | 0.84 | CA1 (0.56) | CA1CA2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28827921 | 0.84 | SMN1; SMN2 (0.61) | CA1CA2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL478510 | 0.81 | KMT2A (0.63) | CA1CA2MAPTKMT2ATSHR | |
| SCHEMBL11946585 | 0.81 | CA1 (0.53) | CA1CA2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL2363101 | 0.80 | MAPT (0.44) | CA1CA2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6548631 | 0.79 | CA1 (0.64) | CA1CA2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1854840 | 0.79 | KMT2A (0.66) | CA1CA2MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003040120-A1 | PROCESS FOR THE PREPARATION OF DRONEDARONE | ISP INVESTMENTS INC. (US) | 2003-05-15 | — | — | WO | disclosed |