SCHEMBL7262175

SCHEMBL7262175

CC1(c2ccc(O)cc2)COc2cc(O)ccc2C1c1ccc(C[C@H](N)C(=O)OCCCCCCC(CCCC(F)(F)C(F)(F)F)C(=O)O)cc1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.37
TYR P14679 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7258205 1.00 ESR1 (0.37) ESR1TYR
SCHEMBL7257957 1.00 ESR1 (0.37) ESR1TYR
SCHEMBL7262416 0.99 ESR1 (0.36) ESR1TYR
SCHEMBL5856046 0.88 ESR1 (0.40) ESR1
SCHEMBL5854563 0.88 ESR1 (0.40) ESR1
SCHEMBL5855904 0.88 ESR1 (0.40) ESR1
SCHEMBL5855606 0.87 ESR1 (0.39) ESR1
SCHEMBL5854160 0.84 ESR1 (0.38) ESR1
SCHEMBL5856044 0.78 ESR1 (0.47) ESR1
SCHEMBL5855481 0.78 ESR1 (0.47) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6645951-B1 Antiestrogens for treating breast cancer CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-11-11 US claimed