Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.69 |
| ▸ | GSK3B | P49841 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293317 | 0.84 | KMT2A (0.73) | GSK3AGSK3BKMT2AMEN1GAA | |
| SCHEMBL8320050 | 0.82 | SMN1; SMN2 (0.73) | GSK3AGSK3BKMT2AMEN1GAA | |
| SCHEMBL29234520 | 0.82 | GSK3A (0.69) | GSK3AGSK3BKMT2AMEN1GAA | |
| SCHEMBL5311390 | 0.82 | GSK3A (0.69) | GSK3AGSK3BKMT2AMEN1GAA | |
| SCHEMBL3318940 | 0.81 | GSK3A (1.00) | GSK3AGSK3BKMT2AMEN1GAA | |
| SCHEMBL5182321 | 0.80 | GSK3A (0.66) | GSK3AGSK3BKMT2AMEN1GAA | |
| SCHEMBL30953279 | 0.80 | GSK3A (0.71) | GSK3AGSK3BKMT2AMEN1GAA | |
| SCHEMBL378362 | 0.79 | GSK3A (0.65) | GSK3AGSK3BKMT2AMEN1GAA | |
| SCHEMBL4455461 | 0.79 | GSK3A (0.69) | GSK3AGSK3BKMT2AMEN1GAA | |
| SCHEMBL7267266 | 0.78 | GSK3A (0.63) | GSK3AGSK3BKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6667334-B1 | Inhibitors of adhesion and migration of leukocytes and/or antagonists of adhesion receptor VLA-4 belonging to integrins group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-23 | — | — | US | disclosed |