Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.72 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.72 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099962 | 1.00 | ITGB1 (0.72) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL7101237 | 0.89 | ITGB1 (0.82) | ITGB1ITGA4 | |
| SCHEMBL7101244 | 0.89 | ITGB1 (0.82) | ITGB1ITGA4 | |
| SCHEMBL7194706 | 0.83 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL7263425 | 0.83 | ITGB1 (0.63) | ITGB1ITGA4 | |
| SCHEMBL7102778 | 0.83 | ITGB1 (0.68) | ITGB1ITGA4 | |
| SCHEMBL7105896 | 0.83 | ITGB1 (0.65) | ITGB1ITGA4 | |
| SCHEMBL7102786 | 0.83 | ITGB1 (0.68) | ITGB1ITGA4 | |
| SCHEMBL7105903 | 0.83 | ITGB1 (0.65) | ITGB1ITGA4 | |
| SCHEMBL7103667 | 0.83 | ITGB1 (0.67) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518283-B1 | To modify integrin function in such a way as to beneficially modulate cell adhesion | CELLTECH R&D LIMITED (GB) | 2003-02-11 | — | — | US | disclosed |