Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.62 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263202 | 1.00 | ITGB1 (0.62) | ITGB1ITGA4MEN1KMT2AHPGD | |
| SCHEMBL7100894 | 0.88 | ITGB1 (0.64) | ITGB1ITGA4 | |
| SCHEMBL7100888 | 0.88 | ITGB1 (0.64) | ITGB1ITGA4 | |
| SCHEMBL7103669 | 0.85 | ITGB1 (0.67) | ITGB1ITGA4 | |
| SCHEMBL7103667 | 0.85 | ITGB1 (0.67) | ITGB1ITGA4 | |
| SCHEMBL7105636 | 0.85 | ITGB1 (0.67) | ITGB1ITGA4 | |
| SCHEMBL7105631 | 0.85 | ITGB1 (0.67) | ITGB1ITGA4 | |
| SCHEMBL7107384 | 0.85 | ITGB1 (0.61) | ITGB1ITGA4 | |
| SCHEMBL7107392 | 0.85 | ITGB1 (0.61) | ITGB1ITGA4 | |
| SCHEMBL7264369 | 0.84 | ITGB1 (0.61) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518283-B1 | To modify integrin function in such a way as to beneficially modulate cell adhesion | CELLTECH R&D LIMITED (GB) | 2003-02-11 | — | — | US | disclosed |