Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.59 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264095 | 1.00 | ITGB1 (0.59) | ITGB1ITGA4FAAHRAB9A | |
| SCHEMBL7099505 | 0.91 | ITGB1 (0.60) | ITGB1ITGA4 | |
| SCHEMBL7099501 | 0.91 | ITGB1 (0.60) | ITGB1ITGA4 | |
| SCHEMBL7105795 | 0.91 | ITGB1 (0.60) | ITGB1ITGA4RAB9A | |
| SCHEMBL7105799 | 0.91 | ITGB1 (0.60) | ITGB1ITGA4RAB9A | |
| SCHEMBL7263253 | 0.85 | ITGB1 (0.66) | ITGB1ITGA4 | |
| SCHEMBL7263254 | 0.85 | ITGB1 (0.66) | ITGB1ITGA4 | |
| SCHEMBL7100894 | 0.80 | ITGB1 (0.64) | ITGB1ITGA4RAB9A | |
| SCHEMBL7100888 | 0.80 | ITGB1 (0.64) | ITGB1ITGA4RAB9A | |
| SCHEMBL7259410 | 0.78 | ITGB1 (0.64) | ITGB1ITGA4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518283-B1 | To modify integrin function in such a way as to beneficially modulate cell adhesion | CELLTECH R&D LIMITED (GB) | 2003-02-11 | — | — | US | disclosed |