Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 5/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272500 | 0.90 | ACE (0.50) | ACELMNALTA4HCTRB1ACE2 | |
| SCHEMBL7264861 | 0.88 | ACE (0.53) | ACELMNALTA4HCTRB1ACE2 | |
| Cyclohexylamine SCHEMBL10724749 | 0.82 | ACE (0.47) | ACELMNALTA4HCTRB1ACE2 | |
| SCHEMBL10655550 | 0.81 | ACE (0.52) | ACELMNALTA4HACE2SMN1; SMN2 | |
| SCHEMBL10658161 | 0.81 | ACE (0.52) | ACELMNALTA4HACE2SMN1; SMN2 | |
| SCHEMBL7273945 | 0.81 | ACE (0.61) | ACELTA4HACE2 | |
| SCHEMBL10657952 | 0.80 | ACE (0.54) | ACELMNALTA4HACE2SMN1; SMN2 | |
| Water SCHEMBL7272188 | 0.80 | ACE (0.60) | ACELTA4HACE2 | |
| SCHEMBL10660541 | 0.79 | ACE (0.54) | ACELMNALTA4HSMN1; SMN2 | |
| SCHEMBL7368526 | 0.78 | ACE (0.51) | ACELMNALTA4HACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185390-B1 | TRIPEPTIDYL-ARGININALDEHYDE, PROCESS FOR ITS PREPARATION AND MEDICAMENTS THEREOF, AS WELL AS N-(MONOALKYL) AND N,N-DI-(ALKYL)-XXX-L-PROLINE DIPEPTIDE | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-10-02 | — | — | EP | disclosed |
| US-4703036-A | ANTICOAGULANTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-10-27 | — | — | US | disclosed |
| EP-0185390-A2 | Tripeptidyl-argininaldehyde, process for its preparation and medicaments thereof, as well as N-(monoalkyl) and N,N-di-(alkyl)-Xxx-L-proline dipeptide | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-06-25 | — | — | EP | disclosed |