⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldoxime SCHEMBL8915953 | 0.67 | — | — | |
| Formaldoxime SCHEMBL8584089 | 0.62 | — | — | |
| Formaldoxime SCHEMBL14992435 | 0.62 | — | — | |
| Formaldoxime SCHEMBL27582278 | 0.62 | — | — | |
| Formaldoxime SCHEMBL27699389 | 0.62 | — | — | |
| Formaldoxime SCHEMBL7594534 | 0.62 | — | — | |
| Formaldoxime SCHEMBL19715265 | 0.62 | — | — | |
| Formaldoxime SCHEMBL27802081 | 0.62 | — | — | |
| Formaldoxime SCHEMBL11805691 | 0.62 | — | — | |
| Formaldoxime SCHEMBL28143941 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6558633-B1 | Chemical reaction apparatus and methods | ISIS PHARMACEUTICALS, INC. | 2003-05-06 | — | — | US | disclosed |
| US-20010028866-A1 | Chemical synthesis apparatus employing a droplet generator | ISIS PHARMACEUTICALS, INC. | 2001-10-11 | — | — | US | disclosed |
| US-6277334-B1 | TO PREPARE OLIGOMERS AND LIBRARIES OF CHEMICAL SPECIES. | ISIS PHARMACEUTICALS, INC. | 2001-08-21 | — | — | US | disclosed |
| US-6232317-B1 | DERIVATIVES OF 4-PHENYL-2,3-DIHYDROISOXAZOLONE AND 4-PHENYL-2,4-DIHYDROTRIAZOLONES HAVING METHYLENEOXIMINO GROUP ORTHO POSITION AND PROCESS OF MAKING THEM BY OXIMINATION, OXIDATION, AND HALOGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-15 | — | — | US | disclosed |
| US-5925732-A | CHEMICAL DROPLET GENERATION AND DIRECTION TECHNIQUES ARE EMPLOYED TO PREPARE OLIGOMERS, POLYPEPTIDES, AND NUCLEIC ACIDS, AND LIBRARIES OF CHEMICAL SPECIES | ISIS PHARMACEUTICALS, INC. (US) | 1999-07-20 | — | — | US | disclosed |
| US-5612895-A | Method of rational drug design based on ab initio computer simulation of conformational features of peptides | BALAJI VITUKUDI N (US) | 1997-03-18 | — | — | US | disclosed |
| US-5579250-A | COMPUTER-ASSISTED METHOD | BALAJI VITUKUDI N (US) | 1996-11-26 | — | — | US | disclosed |
| US-5331573-A | Method of design of compounds that mimic conformational features of selected peptides | TEXAS BIOTECHNOLOGY CORPORATION | 1994-07-19 | — | — | US | disclosed |
| EP-0495963-A4 | IMPROVED HYPOGLYCEMICS | — | 1993-09-01 | — | — | EP | disclosed |
| EP-0495963-A1 | IMPROVED HYPOGLYCEMICS | AMYLIN PHARMACEUTICALS, INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| WO-1992003148-A1 | IMPROVED HYPOGLYCEMICS | AMYLIN CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |