SCHEMBL7265296

SCHEMBL7265296

CCCCCCc1cnc(-c2ccc(OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc2)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.50
RAB9A P51151 7/20 0.47
MAPT P10636 6/20 0.47
SMN1; SMN2 Q16637 6/20 0.47
USP2 O75604 3/20 0.47
KDM4E B2RXH2 2/20 0.47
HSD17B10 Q99714 2/20 0.47
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 2/20 0.47
KMT2A Q03164 2/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.44
NPC1 O15118 5/20 0.43
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
STAT3 P40763 1/20 0.38
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8075875 1.00 RARB (0.50) RARBRAB9AMAPTSMN1; SMN2USP2
SCHEMBL8076144 1.00 RARB (0.50) RARBRAB9AMAPTSMN1; SMN2USP2
SCHEMBL8075811 1.00 RARB (0.50) RARBRAB9AMAPTSMN1; SMN2USP2
SCHEMBL8074170 1.00 RARB (0.50) RARBRAB9AMAPTSMN1; SMN2USP2
SCHEMBL8076156 1.00 RARB (0.50) RARBRAB9AMAPTSMN1; SMN2USP2
SCHEMBL8080774 1.00 RARB (0.50) RARBRAB9AMAPTSMN1; SMN2USP2
SCHEMBL8075884 1.00 RARB (0.50) RARBRAB9AMAPTSMN1; SMN2USP2
SCHEMBL8066021 0.95 RARB (0.52) RARBRAB9AMAPTSMN1; SMN2USP2
SCHEMBL8076150 0.95 RARB (0.52) RARBRAB9AMAPTSMN1; SMN2USP2
SCHEMBL7756937 0.94 RARB (0.45) RARBRAB9AMAPTSMN1; SMN2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5417883-A Electrooptical display device MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-23 US claimed
EP-1183567-B1 METHOD OF MAKING ACTIVE SUBSTRATES FOR COLOR LIQUID CRYSTAL DISPLAYS 3M INNOVATIVE PROPERTIES CO (US) 2003-05-07 EP disclosed
US-20010010884-A1 Active substrates for color displays 3M INNOVATIVE PROPERTIES COMPANY 2001-08-02 US disclosed
US-6221543-B1 THERMALLY MASS TRANSFERRING PLURALITY OF COLOR FILTERS TO SELECTED PORTIONS OF SUBSTRATE, EACH COLOR FILTER COMPRISING A COLORANT IN A CROSSLINKABLE COMPOSITION, INSPECTING COLOR FILTERS AFTER TRANSFERRING AND PRIOR TO CROSSLINKING, WASHING 3M INNOVATIVES PROPERTIES 2001-04-24 US disclosed
EP-0646636-B1 Liquid crystal compounds having a fluoroether terminal portion MINNESOTA MINING & MFG (US) 2000-08-23 EP disclosed
EP-0755425-B1 PROCESS FOR CONTROLLING LAYER SPACING IN MIXTURES OF SMECTIC LIQUID CRYSTAL COMPOUNDS MINNESOTA MINING & MFG (US) 1999-09-22 EP disclosed
EP-0755425-A1 PROCESS FOR CONTROLLING LAYER SPACING IN MIXTURES OF SMECTIC LIQUID CRYSTAL COMPOUNDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-01-29 EP disclosed
WO-1995027765-A1 PROCESS FOR CONTROLLING LAYER SPACING IN MIXTURES OF SMECTIC LIQUID CRYSTAL COMPOUNDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-10-19 WO disclosed
US-5417883-A Electrooptical display device MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-23 US disclosed
EP-0646636-A1 Liquid crystal compounds having a fluoroether terminal portion MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-05 EP disclosed