Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL7267250 | 0.93 | CYP3A4 (0.50) | CYP1A2CYP3A4RECQLMAPK1CYP2C19 | |
| Fumaric Acid SCHEMBL7267252 | 0.93 | CYP3A4 (0.50) | CYP1A2CYP3A4RECQLMAPK1CYP2C19 | |
| Hydrochloric Acid SCHEMBL9511381 | 0.85 | MAPK1 (0.56) | CYP1A2CYP3A4RECQLMAPK1CYP2C19 | |
| SCHEMBL7273963 | 0.84 | KMT2A (0.46) | CYP1A2CYP3A4RECQLMAPK1CYP2C19 | |
| Hydrochloric Acid SCHEMBL9678356 | 0.81 | MAPK1 (0.48) | CYP1A2CYP3A4RECQLMAPK1CYP2C19 | |
| SCHEMBL10561803 | 0.80 | CYP3A4 (0.48) | CYP1A2CYP3A4RECQLMAPK1CYP2C19 | |
| SCHEMBL9512547 | 0.76 | CYP3A4 (0.54) | CYP1A2CYP3A4RECQLMAPK1CYP2C19 | |
| Hydrochloric Acid SCHEMBL9172426 | 0.74 | MAPK1 (0.47) | CYP1A2CYP3A4RECQLMAPK1CYP2C19 | |
| SCHEMBL27661323 | 0.74 | TAAR1 (0.50) | CYP1A2CYP3A4RECQLMAPK1CYP2C19 | |
| SCHEMBL9776961 | 0.74 | CHRM1 (0.44) | CYP1A2CYP3A4RECQLMAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279937-B1 | 2-AMINOACETAMIDE DERIVATIVES | FISONS CORPORATION (US) | 1991-10-09 | — | — | EP | claimed |
| EP-0427427-A2 | Use of arylalkylamides in the treatment of neurodegenerative diseases | FISONS CORPORATION (US) | 1991-05-15 | — | — | EP | claimed |
| EP-0427427-A2 | Use of arylalkylamides in the treatment of neurodegenerative diseases | FISONS CORPORATION (US) | 1991-05-15 | — | — | EP | disclosed |