Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 3/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.79 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PDE3B | Q13370 | 15/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 15/20 | 0.57 |
| ▸ | SLFN12 | Q8IYM2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474001 | 0.89 | GALR3 (0.76) | GALR3MAPTSMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7266967 | 0.88 | GALR3 (0.73) | GALR3MAPTSMN1; SMN2THRBALDH1A1 | |
| SCHEMBL16157214 | 0.88 | MAPT (1.00) | GALR3MAPTSMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7321514 | 0.87 | GALR3 (0.77) | GALR3MAPTSMN1; SMN2THRBALDH1A1 | |
| Iodide SCHEMBL10474072 | 0.87 | GALR3 (0.74) | GALR3MAPTSMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7273931 | 0.87 | GALR3 (0.79) | GALR3MAPTSMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7267555 | 0.86 | GALR3 (0.81) | GALR3MAPTSMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7315454 | 0.86 | MAPT (0.71) | GALR3MAPTSMN1; SMN2THRBALDH1A1 | |
| SCHEMBL16156975 | 0.86 | MAPT (0.71) | GALR3MAPTSMN1; SMN2THRBALDH1A1 | |
| SCHEMBL16156961 | 0.85 | MAPT (0.79) | GALR3MAPTSMN1; SMN2THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327800-B1 | 6-PHENYLDIHYDRO-3(2H)-PYRIDAZINONES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | HEUMANN PHARMA GMBH & CO (DE) | 1992-05-27 | — | — | EP | disclosed |
| US-4954501-A | INOTROPIC AGENTS | HEUMANN PHARMA GMBH & CO. (DE) | 1990-09-04 | — | — | US | disclosed |
| EP-0327800-A2 | 6-Phenyldihydro-3(2H)-pyridazinones, process for their preparation and medicines containing these compounds | HEUMANN PHARMA GMBH & CO (DE) | 1989-08-16 | — | — | EP | disclosed |