Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 14/20 | 0.52 |
| ▸ | DRD2 | P14416 | 6/20 | 0.52 |
| ▸ | DRD5 | P21918 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266679 | 0.86 | DRD1 (0.54) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL7268264 | 0.84 | DRD1 (0.44) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL7266471 | 0.84 | DRD1 (0.54) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| Hydrochloric Acid SCHEMBL7290848 | 0.83 | DRD1 (0.53) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL7276990 | 0.83 | DRD1 (0.56) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL7267025 | 0.80 | DRD1 (0.50) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| Hydrochloric Acid SCHEMBL10413117 | 0.79 | DRD1 (0.50) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL10414549 | 0.77 | DRD1 (0.49) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL7267640 | 0.76 | DRD1 (0.53) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| Hydrochloric Acid SCHEMBL7299250 | 0.76 | DRD1 (0.56) | DRD1DRD2DRD5HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324610-B1 | Thieno[2,3-d]azepine derivatives, process for their preparation and pharmaceutical compositions containing them | LILLY INDUSTRIES LTD (GB) | 1994-04-13 | — | — | EP | disclosed |
| US-4904653-A | Thieno[2,3-O]azepine compounds and CNS affecting use thereof | LILLY INDUSTRIES LIMITED (GB) | 1990-02-27 | — | — | US | disclosed |
| EP-0324610-A2 | Thieno[2,3-d]azepine derivatives, process for their preparation and pharmaceutical compositions containing them | LILLY INDUSTRIES LIMITED (GB) | 1989-07-19 | — | — | EP | disclosed |