Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 3/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12789448 | 0.86 | KMT2A (0.48) | KMT2ATAAR1MEN1EPHX1TACR1 | |
| SCHEMBL8865987 | 0.84 | MEN1 (0.38) | KMT2ATAAR1MEN1EPHX1TACR1 | |
| SCHEMBL8865889 | 0.84 | ACP3 (0.42) | KMT2ATAAR1MEN1ALDH1A1 | |
| SCHEMBL7430254 | 0.82 | KMT2A (0.46) | KMT2ATAAR1MEN1EPHX1ALDH1A1 | |
| SCHEMBL24576212 | 0.80 | KMT2A (0.43) | KMT2ATAAR1MEN1EPHX1TACR1 | |
| SCHEMBL8868980 | 0.79 | ACP3 (0.47) | KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL5565812 | 0.77 | KMT2A (0.52) | KMT2ATAAR1MEN1EPHX1ALDH1A1 | |
| SCHEMBL5564916 | 0.77 | KMT2A (0.52) | KMT2ATAAR1MEN1EPHX1ALDH1A1 | |
| SCHEMBL1911373 | 0.77 | KMT2A (0.52) | KMT2ATAAR1MEN1EPHX1ALDH1A1 | |
| SCHEMBL18269667 | 0.74 | HTR2A (0.48) | KMT2ATAAR1MEN1ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382683-A | 2-aminopropanamide derivatives | FISONS CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0326240-B1 | 2-Amino acetamide derivatives | FISONS CORP (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5093524-A | 2-(alkylamino)acetamide derivatives | FISONS CORPORATION (US) | 1992-03-03 | — | — | US | disclosed |
| EP-0279937-B1 | 2-AMINOACETAMIDE DERIVATIVES | FISONS CORPORATION (US) | 1991-10-09 | — | — | EP | disclosed |
| US-5047541-A | 2-azacyclocarboxamide derivatives | FISONS CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |
| EP-0401253-A1 | 2-AMINO ACETAMIDE DERIVATIVES | FISONS CORPORATION (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4871872-A | 2-[(2-aminoacetyl)amino]acetamide derivatives | FISONS CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0326240-A1 | 2-Amino acetamide derivatives | FISONS CORPORATION (US) | 1989-08-02 | — | — | EP | disclosed |
| WO-1989006646-A1 | 2-AMINO ACETAMIDE DERIVATIVES | FISONS CORPORATION (US) | 1989-07-27 | — | — | WO | disclosed |
| EP-0279937-A1 | 2-Aminoacetamide derivatives | FISONS CORPORATION (US) | 1988-08-31 | — | — | EP | disclosed |
| EP-0278089-A2 | 2-Azacyclocarboxamide derivatives | FISONS CORPORATION (a Massachusetts corporation) (US) | 1988-08-17 | — | — | EP | disclosed |