Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.59 |
| ▸ | ECE1 | P42892 | 4/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 9/20 | 0.46 |
| ▸ | MMP1 | P03956 | 4/20 | 0.46 |
| ▸ | MMP3 | P08254 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267929 | 1.00 | MME (0.59) | MMEECE1CTSLCTSSANPEP | |
| SCHEMBL7266769 | 0.84 | MME (0.56) | MMEECE1CTSLCTSSANPEP | |
| SCHEMBL7266761 | 0.84 | MME (0.56) | MMEECE1CTSLCTSSANPEP | |
| SCHEMBL7266764 | 0.80 | MME (0.51) | MMEECE1CTSLCTSSANPEP | |
| SCHEMBL7267538 | 0.79 | MME (0.50) | MMEECE1HDAC3HDAC4HDAC1 | |
| SCHEMBL7266278 | 0.78 | HRH4 (0.48) | MMEECE1ANPEPHDAC1HDAC2 | |
| SCHEMBL6443866 | 0.77 | MME (0.55) | MMEECE1MMP2MMP1MMP3 | |
| SCHEMBL6443858 | 0.77 | MME (0.55) | MMEECE1MMP2MMP1MMP3 | |
| SCHEMBL7266079 | 0.76 | MME (0.47) | MMEECE1HDAC3HDAC4HDAC1 | |
| SCHEMBL7280278 | 0.76 | MME (0.47) | MMEECE1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309766-B1 | N-acylamino acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5506356-A | RENIN INHIBITORS; HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| US-5481036-A | RENIN INHIBITORS, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| US-5319082-A | N-acylamino acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5240924-A | Dipeptide hypotensives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| US-5122523-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |