Styrene

Styrene

SCHEMBL726846

C=CC=CC=C(C)C(=O)O.C=Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.50
ALDH1A1 P00352 2/20 0.47
TSHR P16473 2/20 0.47
PTGS1 P23219 1/20 0.42
HTT P42858 1/20 0.39
GLA P06280 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PTGS2 P35354 1/20 0.36
CYP3A4 P08684 1/20 0.35
GAA P10253 1/20 0.35
CYP2C9 P11712 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
RECQL P46063 1/20 0.33
APEX1 P27695 1/20 0.33
AKR1C1 Q04828 1/20 0.33
PSMD14 O00487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL451196 0.87 AKR1C3 (0.50) AKR1C3ALDH1A1TSHRGLATDP1
SCHEMBL768990 0.82 PTGS1 (0.58) AKR1C3ALDH1A1TSHRPTGS1TDP1
SCHEMBL12418030 0.82 PTGS1 (0.58) AKR1C3ALDH1A1TSHRPTGS1TDP1
Styrene SCHEMBL10355583 0.81 AKR1C3 (0.45) AKR1C3ALDH1A1TSHRPTGS1HTT
Butadiene SCHEMBL9678114 0.81 AKR1C3 (0.52) AKR1C3ALDH1A1GLATDP1CYP3A4
Styrene SCHEMBL93464 0.81 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL11043969 0.81 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL1126458 0.81 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL238869 0.80 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL134355 0.80 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRHTTGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2585526-B1 RUBBER COMPOSITION COMPRISING A THERMOPLASTIC REINFORCING FILLER AND A COMPATIBILISING AGENT MICHELIN & CIE (FR) 2015-12-30 EP claimed
EP-2585526-A1 RUBBER COMPOSITION COMPRISING A THERMOPLASTIC FILLER AND COMPATIBILIZER Compagnie Générale des Etablissements Michelin (FR) 2013-05-01 EP claimed
WO-2011161222-A1 RUBBER COMPOSITION COMPRISING A THERMOPLASTIC FILLER AND COMPATIBILIZER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2011-12-29 WO claimed
US-5250390-A Block polymer having hydrophilic rigid and hydrophobic flexible segments and a photopolymerizable unsaturated compound; resistance to water-dilutable printing inks HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-05 US disclosed
EP-0196072-A2 Iodine compound activation of autodepositing baths AMCHEM PRODUCTS, INC. (US) 1986-10-01 EP disclosed