Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | FCER2 | P06734 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21065923 | 1.00 | PTPN1 (0.46) | PTPN1EPHX1CPA1FCER2MMP1 | |
| SCHEMBL13711063 | 0.92 | EPHX1 (0.53) | EPHX1FCER2MMP1HPGDSPPARG | |
| SCHEMBL3596182 | 0.92 | EPHX1 (0.53) | EPHX1FCER2MMP1HPGDSPPARG | |
| SCHEMBL989218 | 0.92 | EPHX1 (0.53) | EPHX1FCER2MMP1HPGDSPPARG | |
| Hydrochloric Acid SCHEMBL6895586 | 0.90 | EPHX1 (0.51) | EPHX1FCER2MMP1HPGDSPPARG | |
| Trifluoroacetic Acid SCHEMBL2587894 | 0.83 | PTPN1 (0.52) | PTPN1FCER2MMP1RENACE | |
| SCHEMBL17550583 | 0.81 | FCER2 (0.57) | PTPN1FCER2MMP1RENACE | |
| SCHEMBL21326284 | 0.81 | EPHX1 (0.49) | PTPN1EPHX1CPA1FCER2MMP1 | |
| SCHEMBL21326281 | 0.81 | EPHX1 (0.49) | PTPN1EPHX1CPA1FCER2MMP1 | |
| SCHEMBL8318346 | 0.80 | TAAR1 (0.52) | TAAR1SLC18A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3501546-A2 | CYSTEINE DRUG CONJUGATES AND USE OF SAME | Seattle Genetics, Inc. (US) | 2019-06-26 | — | — | EP | disclosed |
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| EP-0376012-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |