Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.66 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.66 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | XIAP | P98170 | 1/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | CPA1 | P15085 | 6/20 | 0.52 |
| ▸ | CPA3 | P15088 | 3/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | CPB1 | P15086 | 1/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.52 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL305323 | 0.89 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1CYP1A2ALPI | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL2919214 | 0.89 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1CYP1A2ALPI | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL7289849 | 0.89 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1CYP1A2ALPI | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL4755513 | 0.89 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1CYP1A2ALPI | |
| SCHEMBL14318901 | 0.88 | SLC1A3 (0.58) | SLC1A3SLC1A2SLC1A1CYP1A2ALPI | |
| SCHEMBL3866544 | 0.85 | SLC1A3 (0.63) | SLC1A3SLC1A2SLC1A1CYP1A2ALPI | |
| SCHEMBL7436297 | 0.85 | SLC1A3 (0.63) | SLC1A3SLC1A2SLC1A1CYP1A2ALPI | |
| SCHEMBL3867023 | 0.85 | SLC1A3 (0.63) | SLC1A3SLC1A2SLC1A1CYP1A2ALPI | |
| SCHEMBL2243422 | 0.85 | SLC1A3 (0.63) | SLC1A3SLC1A2SLC1A1CYP1A2ALPI | |
| SCHEMBL24252143 | 0.83 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1CYP1A2ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839798-A2 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |