Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763305 | 0.79 | TSHR (0.47) | TSHRTDP1L3MBTL1ALDH1A1PPARG | |
| SCHEMBL2554577 | 0.79 | TSHR (0.47) | TSHRTDP1L3MBTL1ALDH1A1PPARG | |
| SCHEMBL14039046 | 0.77 | TSHR (0.46) | TSHRTDP1L3MBTL1ALDH1A1PPARG | |
| SCHEMBL15998203 | 0.77 | TSHR (0.46) | TSHRTDP1L3MBTL1ALDH1A1PPARG | |
| SCHEMBL17041841 | 0.77 | TSHR (0.48) | TSHRTDP1L3MBTL1ALDH1A1PPARG | |
| SCHEMBL7269313 | 0.77 | TSHR (0.46) | TSHRTDP1L3MBTL1ALDH1A1PPARG | |
| SCHEMBL10141959 | 0.77 | TSHR (0.46) | TSHRTDP1L3MBTL1ALDH1A1PPARG | |
| SCHEMBL8862687 | 0.76 | TDP1 (0.49) | TSHRTDP1L3MBTL1ALDH1A1PPARG | |
| SCHEMBL2530416 | 0.76 | TSHR (0.42) | TSHRTDP1L3MBTL1ALDH1A1PPARG | |
| SCHEMBL16996644 | 0.76 | TDP1 (0.49) | TSHRTDP1L3MBTL1ALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377139-B1 | N-substituted acylamino acid compounds, process for their production and their use | BANYU PHARMA CO LTD (JP) | 1995-07-12 | — | — | EP | disclosed |
| US-5424309-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0377139-A1 | N-substituted acylamino acid compounds, process for their production and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1990-07-11 | — | — | EP | disclosed |