Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17202758 | 0.92 | SPHK1 (0.47) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL1065953 | 0.92 | SPHK1 (0.47) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL1065955 | 0.92 | SPHK1 (0.47) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL22318963 | 0.92 | SPHK1 (0.47) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL1065951 | 0.92 | SPHK1 (0.47) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL1066083 | 0.92 | SPHK1 (0.47) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL17202997 | 0.88 | SPHK1 (0.45) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL10211341 | 0.88 | SPHK1 (0.45) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL11968693 | 0.88 | SPHK1 (0.45) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL17202995 | 0.88 | SPHK1 (0.45) | SPHK1HSD11B2BRD4CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377139-B1 | N-substituted acylamino acid compounds, process for their production and their use | BANYU PHARMA CO LTD (JP) | 1995-07-12 | — | — | EP | disclosed |
| US-5424309-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0377139-A1 | N-substituted acylamino acid compounds, process for their production and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1990-07-11 | — | — | EP | disclosed |