SCHEMBL726972

SCHEMBL726972

O=C(O)c1oc2c(c1C(=O)O)CCCC2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
GAA P10253 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TSHR P16473 2/20 0.38
POLB P06746 3/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
ALDH1A1 P00352 5/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
PTPN1 P18031 2/20 0.34
PTPRC P08575 1/20 0.34
PTPN2 P17706 1/20 0.34
PTPRB P23467 1/20 0.34
PTPRE P23469 1/20 0.34
PTPN6 P29350 1/20 0.34
MAPT P10636 4/20 0.34
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15288258 0.96 CYP1A2 (0.50) CYP1A2GAAHSD17B10TSHRPOLB
SCHEMBL14895573 0.87 CYP1A2 (0.54) CYP1A2GAAHSD17B10LMNA
SCHEMBL30060372 0.78 TSHR (0.54) GAAHSD17B10TSHRPOLBNPC1
SCHEMBL846899 0.75 CYP1A2 (0.48) CYP1A2GAAHSD17B10TSHRPOLB
SCHEMBL22775033 0.73 TSHR (0.40) GAAHSD17B10TSHRPOLBNPC1
SCHEMBL17144961 0.73 CYP1A2 (0.46) CYP1A2GAAHSD17B10TSHRPOLB
SCHEMBL1258695 0.71 PTPN1 (0.42) GAAHSD17B10TSHRPOLBNPC1
SCHEMBL849074 0.70 CYP1A2 (0.48) CYP1A2GAAHSD17B10TSHRPOLB
SCHEMBL1582401 0.69 CYP1A2 (1.00) CYP1A2KMT2AMEN1
SCHEMBL5573410 0.66 PTPN1 (0.43) GAATSHRPOLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10968345-B2 Polyester composition NOVAMONT S.P.A. (IT) 2021-04-06 US disclosed
US-9676902-B2 Aliphatic-aromatic copolyesters and their mixtures NOVAMONT S.P.A. (IT) 2017-06-13 US disclosed
EP-2576653-B1 ALIPHATIC-AROMATIC COPOLYESTERS AND THEIR MIXTURES NOVAMONT SPA (IT) 2016-03-02 EP disclosed
EP-2655514-B1 POLYESTER COMPOSITION NOVAMONT SPA (IT) 2015-01-28 EP disclosed
EP-2655514-A1 POLYESTER COMPOSITION Novamont S.p.A. (IT) 2013-10-30 EP disclosed
US-20130281560-A1 POLYESTER COMPOSITION NOVAMONT S.P.A. (IT) 2013-10-24 US disclosed
EP-2576653-A1 ALIPHATIC-AROMATIC COPOLYESTERS AND THEIR MIXTURES Novamont S.p.A. (IT) 2013-04-10 EP disclosed
US-20130071588-A1 ALIPHATIC-AROMATIC COPOLYESTERS AND THEIR MIXTURES NOVAMONT S.P.A. (IT) 2013-03-21 US disclosed
WO-2012085238-A1 POLYESTER COMPOSITION NOVAMONT S.P.A. (IT) 2012-06-28 WO disclosed
WO-2011147806-A1 ALIPHATIC-AROMATIC COPOLYESTERS AND THEIR MIXTURES. NOVAMONT S.P.A. (IT) 2011-12-01 WO disclosed