Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3012370 | 0.89 | MAOB (0.64) | MAOAMAOBHTTEPHX2CYP11B1 | |
| SCHEMBL31374905 | 0.84 | HDAC1 (0.53) | MAOAMAOBHTTLMNAKMT2A | |
| SCHEMBL14565028 | 0.76 | MAOB (0.57) | MAOAMAOBHTTALDH1A1LMNA | |
| SCHEMBL14565123 | 0.75 | MAOB (0.56) | MAOAMAOBHTTALDH1A1LMNA | |
| SCHEMBL10509516 | 0.75 | HTT (0.59) | MAOAMAOBHTTALDH1A1LMNA | |
| SCHEMBL30199790 | 0.75 | HTT (0.59) | MAOAMAOBHTTALDH1A1LMNA | |
| SCHEMBL3601956 | 0.75 | HTT (0.59) | MAOAMAOBHTTALDH1A1LMNA | |
| SCHEMBL15875502 | 0.75 | HTT (0.59) | MAOAMAOBHTTALDH1A1LMNA | |
| SCHEMBL1332876 | 0.75 | HTT (0.59) | MAOAMAOBHTTALDH1A1LMNA | |
| SCHEMBL7454625 | 0.75 | HTT (0.59) | MAOAMAOBHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411751-A1 | Renin inhibitory peptides | Beecham Group p.l.c. (GB) | 1991-02-06 | — | — | EP | disclosed |