⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286311 | 1.00 | — | — | |
| SCHEMBL7270026 | 1.00 | — | — | |
| SCHEMBL7270030 | 1.00 | — | — | |
| SCHEMBL7270039 | 1.00 | — | — | |
| SCHEMBL16232148 | 0.80 | AAK1 (0.37) | — | |
| SCHEMBL16232145 | 0.80 | AAK1 (0.37) | — | |
| SCHEMBL16232147 | 0.80 | AAK1 (0.37) | — | |
| SCHEMBL15360295 | 0.73 | — | — | |
| SCHEMBL30850059 | 0.73 | — | — | |
| SCHEMBL18173881 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |