Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 18/20 | 0.88 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263606 | 1.00 | ACE (0.88) | ACELMNAABCB11MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7273052 | 0.99 | ACE (0.86) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL7264384 | 0.94 | ACE (1.00) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL7270040 | 0.93 | ACE (0.81) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL7263578 | 0.93 | ACE (0.81) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL7263585 | 0.93 | ACE (0.81) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL7265392 | 0.92 | ACE (0.80) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL7265402 | 0.92 | ACE (0.80) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL7263529 | 0.91 | ACE (0.81) | ACELMNAABCB11 | |
| SCHEMBL7270220 | 0.91 | ACE (0.81) | ACELMNAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508727-A | Antihypertensive 2-oxo-imidazolidine derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1985-04-02 | — | — | US | disclosed |
| EP-0095163-A2 | 2-Oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1983-11-30 | — | — | EP | disclosed |