SCHEMBL7270636

SCHEMBL7270636

Fc1ccc(Br)cc1Sc1cc(Br)ccc1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.49
DGAT1 O75907 1/20 0.39
KDM1A O60341 2/20 0.36
KDM1B Q8NB78 1/20 0.36
CYP2A6 P11509 2/20 0.35
ALDH1A1 P00352 4/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
KMT2A Q03164 2/20 0.33
ALOX15 P16050 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
AHR P35869 1/20 0.33
MAPK1 P28482 2/20 0.32
TSHR P16473 1/20 0.32
HSP90AA1 P07900 1/20 0.32
TLR9 Q9NR96 1/20 0.32
S100A4 P26447 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7262565 0.87 POLB (0.47) POLBDGAT1KDM1AKDM1BCYP2A6
SCHEMBL21862048 0.85 PDE7A (0.43) POLBCYP2A6ALDH1A1NPC1RAB9A
SCHEMBL30016123 0.83 POLB (0.45) POLBDGAT1KDM1AKDM1BCYP2A6
SCHEMBL18084500 0.83 POLB (0.45) POLBDGAT1KDM1AKDM1BCYP2A6
SCHEMBL31620868 0.80 POLB (0.42) POLBDGAT1KDM1AKDM1BALDH1A1
SCHEMBL27177082 0.80 POLB (0.42) POLBDGAT1KDM1AKDM1BALDH1A1
SCHEMBL22903168 0.78 POLB (0.41) POLBDGAT1KDM1AKDM1BCYP2A6
SCHEMBL2003379 0.78 SLC6A2 (0.40) POLBDGAT1KDM1AKDM1BCYP2A6
SCHEMBL17985415 0.77 SLC6A4 (0.38) POLBALDH1A1KMT2ASMN1; SMN2SLC6A2
SCHEMBL7263834 0.76 HSP90AA1 (0.44) CYP2A6ALDH1A1KMT2AALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6558276-B1 Improved feeling without impairing intrinsic resilience; core made from rubber composition of a base rubber, an organic peroxide, an alpha, beta unsaturated carboxylic acid, and a bis type halogen-substituted phenyl disulfide SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2003-05-06 US disclosed
US-6241625-B1 A GOLF BALL COMPRISING A COVER MEMBER AND A CORE MEMBER, WHEREIN POLYAMIDE, TERPOLYMER IONOMER CONTAINING ETHYLENE, (METH)ACRYLIC ACID, AND (METH)ACRYLIC ESTER MIXTURES WITH PEROXIDE AND SULFIDE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2001-06-05 US disclosed