Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737429 | 0.89 | MEN1 (0.47) | MEN1KMT2AKDM4CP2RX3ALDH1A1 | |
| SCHEMBL7262693 | 0.85 | SIRT2 (0.32) | CYP2J2 | |
| SCHEMBL1738035 | 0.74 | MEN1 (0.37) | MEN1KMT2AKDM4CRECQLADORA3 | |
| SCHEMBL4581722 | 0.71 | MEN1 (0.45) | MEN1KMT2AKDM4CTGFBR1RAB9A | |
| SCHEMBL1735234 | 0.70 | CYP11B1 (0.37) | — | |
| SCHEMBL5872843 | 0.66 | MEN1 (0.50) | MEN1KMT2AKDM4CP2RX3RAB9A | |
| SCHEMBL14177811 | 0.65 | MEN1 (0.47) | MEN1KMT2AKDM4CP2RX3TGFBR1 | |
| SCHEMBL8865971 | 0.64 | KCNH2 (0.42) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL13670733 | 0.64 | MEN1 (0.59) | MEN1KMT2ARAB9A | |
| SCHEMBL4450050 | 0.63 | MEN1 (0.61) | MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334106-A2 | NOVEL IMIDAZOLE DERIVATIVES, PRODUCTION METHOD THEREOF AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002040484-A2 | NOVEL IMIDAZOLE DERIVATIVES, PRODUCTION METHOD THEREOF AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-23 | — | — | WO | disclosed |