Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30798962 | 0.91 | SLC2A1 (0.76) | SLC2A1ALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL27849455 | 0.87 | SLC2A1 (0.85) | SLC2A1ALDH1A1SMN1; SMN2POLBATM | |
| Hydrochloric Acid SCHEMBL10452642 | 0.86 | SLC2A1 (0.67) | SLC2A1ALDH1A1SMN1; SMN2KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7272231 | 0.86 | SLC2A1 (0.87) | SLC2A1ALDH1A1SMN1; SMN2KMT2APOLB | |
| Hydrochloric Acid SCHEMBL10452455 | 0.86 | SLC2A1 (0.87) | SLC2A1ALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL4615848 | 0.85 | SLC2A1 (0.69) | SLC2A1ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL4616087 | 0.85 | SLC2A1 (0.69) | SLC2A1ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL11811971 | 0.85 | SLC2A1 (0.68) | SLC2A1ALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL7435099 | 0.84 | ATM (0.76) | SLC2A1ALDH1A1SMN1; SMN2KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL7279840 | 0.84 | SLC2A1 (0.72) | SLC2A1ALDH1A1SMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013760-A | Phenylethylamine derivatives and pharmaceutical use | FISONS PLC (GB) | 1991-05-07 | — | — | US | disclosed |
| EP-0117033-B1 | PHARMACEUTICAL FORMULATIONS | FISONS plc (GB) | 1987-09-30 | — | — | EP | disclosed |
| US-4645768-A | TREATMENT OF CARDIOVASCULAR DISORDERS | FISONS PLC (GB) | 1987-02-24 | — | — | US | disclosed |
| EP-0117033-A2 | Pharmaceutical formulations | FISONS plc (GB) | 1984-08-29 | — | — | EP | disclosed |
| EP-0072061-A1 | Amine derivatives, processes for their production and pharmaceutical compositions containing them | FISONS plc (GB) | 1983-02-16 | — | — | EP | disclosed |