Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555026 | 0.84 | HDAC8 (0.59) | KMT2AKDM4EMAPTL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL7272629 | 0.79 | SLC2A1 (0.65) | KMT2AKDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL30691740 | 0.79 | HDAC8 (0.60) | KMT2AKDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL11010923 | 0.79 | MAPT (0.63) | KMT2AKDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL7273578 | 0.79 | ATM (0.66) | KMT2AKDM4ELMNAATMMEN1 | |
| SCHEMBL30691665 | 0.78 | HDAC8 (0.59) | KMT2AKDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL30691785 | 0.78 | HDAC8 (0.59) | KMT2AKDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL22000063 | 0.78 | MAPT (0.81) | KMT2AKDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL30691839 | 0.78 | HDAC8 (0.63) | KMT2AKDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL2877032 | 0.76 | GBA1 (0.57) | KMT2AKDM4EMAPTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375668-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1990-06-27 | — | — | EP | disclosed |
| US-4868306-A | Compounds | FISONS PLC (GB) | 1989-09-19 | — | — | US | disclosed |
| US-4791216-A | Para ethyl amino phenol pharmaceutical compounds | FISONS PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| US-4657929-A | Compounds | FISONS PLC (GB) | 1987-04-14 | — | — | US | disclosed |
| EP-0142283-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1985-05-22 | — | — | EP | disclosed |