Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 7/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | CCR6 | P51684 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281122 | 1.00 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL7272177 | 1.00 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL7271753 | 0.95 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL7271747 | 0.95 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL7280531 | 0.95 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL7433509 | 0.86 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL9594055 | 0.85 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9585679 | 0.82 | HTR2B (0.56) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9586600 | 0.82 | HTR2B (0.56) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9585348 | 0.82 | HTR2B (0.56) | MEN1KMT2ANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202318-A | Antiserotonine, antiemetic agents | SYNTEX (U.S.A.) INC. (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0457243-A1 | Novel tricyclic compounds | SYNTEX (U.S.A.) INC. (US) | 1991-11-21 | — | — | EP | disclosed |