Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.59 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.56 |
| ▸ | CMA1 | P23946 | 7/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537159 | 0.96 | ACE (0.63) | ACEKLK5CMA1F2PRSS1 | |
| SCHEMBL7148899 | 0.96 | ACE (0.63) | ACEKLK5CMA1F2PRSS1 | |
| SCHEMBL7538363 | 0.93 | ACE (0.59) | ACEKLK5CMA1F2PRSS1 | |
| SCHEMBL7539511 | 0.93 | ACE (0.59) | ACEKLK5CMA1F2PRSS1 | |
| SCHEMBL25448062 | 0.91 | ACE (0.57) | ACEKLK5CMA1F2PRSS1 | |
| SCHEMBL6435112 | 0.91 | ACE (0.57) | ACEKLK5CMA1F2PRSS1 | |
| SCHEMBL8366751 | 0.90 | ACE (0.56) | ACEKLK5CMA1F2PRSS1 | |
| SCHEMBL7265619 | 0.90 | PREP (0.57) | ACEKLK5CMA1CTSLFKBP1A | |
| SCHEMBL7321218 | 0.89 | ACE (0.60) | ACEKLK5CMA1F2PRSS1 | |
| SCHEMBL10403794 | 0.89 | ACE (0.56) | ACEKLK5CMA1F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |