Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763737 | 1.00 | PRCP (0.82) | PRCPSMN1; SMN2TSHRCYP3A4MAPT | |
| SCHEMBL11433568 | 0.97 | PRCP (0.87) | PRCPSMN1; SMN2TSHRCYP3A4MAPT | |
| SCHEMBL11331803 | 0.96 | PRCP (0.89) | PRCPSMN1; SMN2TSHRCYP3A4MAPT | |
| SCHEMBL11841484 | 0.96 | PRCP (0.89) | PRCPSMN1; SMN2TSHRCYP3A4MAPT | |
| SCHEMBL10954962 | 0.93 | PRCP (0.75) | PRCPSMN1; SMN2TSHRCYP3A4MAPT | |
| SCHEMBL9277484 | 0.92 | PRCP (0.83) | PRCPSMN1; SMN2TSHRCYP3A4MAPT | |
| SCHEMBL9277796 | 0.89 | PRCP (0.75) | PRCPSMN1; SMN2TSHRCYP3A4MAPT | |
| SCHEMBL9277793 | 0.89 | PRCP (0.75) | PRCPSMN1; SMN2TSHRCYP3A4MAPT | |
| SCHEMBL10952307 | 0.89 | PRCP (0.68) | PRCPSMN1; SMN2TSHRCYP3A4MAPT | |
| SCHEMBL7265572 | 0.88 | TSHR (0.68) | PRCPSMN1; SMN2TSHRCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4636567-A | CNS DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1987-01-13 | — | — | US | disclosed |
| US-4610821-A | CENTRAL NERVOUS SYSTEM, THYROTROPIN RELEASING HORMONE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-09-09 | — | — | US | disclosed |
| US-4564609-A | NERVOUS SYSTEM DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0123444-A1 | 4-Substituted-2-azetidinone compound, process of producing the compounds, and medicaments containing the compounds | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |