⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16341218 | 0.77 | — | — | |
| SCHEMBL2045430 | 0.73 | — | — | |
| SCHEMBL8781774 | 0.68 | — | — | |
| SCHEMBL7289648 | 0.67 | — | — | |
| SCHEMBL2038626 | 0.64 | — | — | |
| SCHEMBL294041 | 0.64 | — | — | |
| SCHEMBL2040056 | 0.64 | — | — | |
| SCHEMBL2041362 | 0.64 | — | — | |
| SCHEMBL7031306 | 0.60 | — | — | |
| SCHEMBL2043715 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321756-B2 | Azole compounds as PIM inhibitors | AMGEN INC. (US) | 2016-04-26 | — | — | US | claimed |
| US-20140187553-A1 | Azole Compounds as PIM Inhibitors | AMGEM INC. (US) | 2014-07-03 | — | — | US | claimed |
| CN-112280567-B | Composition comprising compound functioning as dichromatic pigment | 住友化学株式会社 | 2024-06-25 | — | — | CN | disclosed |
| CN-112280567-A | Composition comprising compound functioning as dichroic pigment | 住友化学株式会社 | 2021-01-29 | — | — | CN | disclosed |
| CN-107250322-B | Composition comprising compound functioning as dichroic pigment | 住友化学株式会社 | 2020-11-27 | — | — | CN | disclosed |
| US-9321756-B2 | Azole compounds as PIM inhibitors | AMGEN INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20140187553-A1 | Azole Compounds as PIM Inhibitors | AMGEM INC. (US) | 2014-07-03 | — | — | US | disclosed |
| CN-1036651-C | Carbostyril derivatives and pharmaceutical composition containing the same | OTSUKA PHARMA CO LTD (JP) | 1997-12-10 | — | — | CN | disclosed |
| EP-0470514-B1 | Carbostyril derivatives and pharmaceutical composition containing the same | OTSUKA PHARMA CO LTD (JP) | 1997-02-19 | — | — | EP | disclosed |
| US-5300513-A | Vasopressin antagonists; vasodilators, hypotensive agents, water diuretics, and platelet agglutination inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| CN-1058779-A | Carbostyril derivative and the pharmaceutical composition that contains this compound | OTSUKA PHARMA CO LTD (JP) | 1992-02-19 | — | — | CN | disclosed |
| EP-0470514-A1 | Carbostyril derivatives and pharmaceutical composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-12 | — | — | EP | disclosed |