Methyl Alcohol

Methyl Alcohol

SCHEMBL727404

CC(=O)OCC(C)OCC(C)O.CO.COCC(C)OCC(C)OC

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
CHRM5 P08912 2/20 0.31
CHRM1 P11229 2/20 0.31
CHRM3 P20309 2/20 0.31
PGR P06401 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
HTR1A P08908 1/20 0.31
CHRNB2 P17787 1/20 0.31
TBXA2R P21731 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CHRNA10 Q9GZZ6 1/20 0.31
CHRNA9 Q9UGM1 1/20 0.31
GALR3 O60755 1/20 0.30
GAA P10253 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29238359 0.94 TDP1 (0.40) TDP1CHRM5CHRM1CHRM3PGR
SCHEMBL727405 0.92 TDP1 (0.35) TDP1CHRM5CHRM1CHRM3PGR
Methyl Alcohol SCHEMBL9849179 0.89 MAPT (0.36) TDP1CHRM5CHRM1CHRM3PGR
SCHEMBL4759657 0.87 CHRM1 (0.36) TDP1CHRM5CHRM1CHRM3PGR
Methoxymethane SCHEMBL3383278 0.87 TDP1 (0.44) TDP1CHRM5CHRM1CHRM3PGR
SCHEMBL487683 0.87 TDP1 (0.38) TDP1CHRM5CHRM1CHRM3PGR
SCHEMBL10277718 0.87 TDP1 (0.38) TDP1CHRM5CHRM1CHRM3PGR
SCHEMBL145637 0.87 TDP1 (0.38) TDP1CHRM5CHRM1CHRM3PGR
SCHEMBL10713829 0.87 TDP1 (0.47) TDP1CHRM5CHRM1CHRM3PGR
SCHEMBL9668977 0.86 TDP1 (0.39) TDP1CHRM1CHRM2CHRM4TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4769408-B2 2011-09-07 JP claimed
US-6765083-B2 TREATING THE CURED POLYMER WITH AN EXTRACTING SOLVENT HAVING SPECIFIED SWELLING OF THE CURED POLYMER, AND HANSEN SOLUBILITY PARAMETERS; SILICONE HYDROGELS FOR CONTACT LENSES JOHNSON & JOHNSON VISION CARE, INC. 2004-07-20 US claimed
JP-2004512939-A 2004-04-30 JP claimed
EP-1358256-A2 SOLVENTS USEFUL IN THE PREPARATION OF POLYMERS CONTAINING HYDROPHILIC AND HYDROPHOBIC MONOMERS Johson & Johnson Vision Care Inc. (US) 2003-11-05 EP claimed
US-20020193559-A1 Solvents useful in the preparation of polymers containing hydrophilic and hydrophobic monomers JOHNSON & JOHNSON VISION CARE, INC. 2002-12-19 US claimed
WO-2002036669-A2 SOLVENTS USEFUL IN THE PREPARATION OF POLYMERS CONTAINING HYDROPHILIC AND HYDROPHOBIC MONOMERS JOHNSON & JOHNSON VISION CARE, INC. (US) 2002-05-10 WO claimed